Cell Culture

E-IP Expan™ Valproic Acid

$99.00

Epigenetic modifier; enhancing protein expression in mammalian cell cultures.

SKU: 70085 Category:

Description

OverviewProduct ApplicationsData and Publications
Valproic acid (VPA): a viable alternative to sodium butyrate for enhancing protein expression in mammalian cell cultures. VPA can increase γ­aminobutyric acid (GABA) levels via inhibition of enzymes involved in GABA metabolism.

Product Name

E-IP Expan™ Valproic Acid

Catalog #

70085

 

Product Applications

This product is designed for use in the following research area(s) as part of the highlighted workflow stage(s).

Workflow Stages for

Human Pluripotent Stem Cell Research

Reprogramming>>Maintenance>>Differentiation

Cell Sourcing and Isolation>>Culture and Cryopreservation>>Differentiation>>Characterization

 

Publications

Göttlicher, M., Minucci, S., Zhu, P., Krämer, O. H., Schimpf, A., Giavara, S., … & Heinzel, T. (2001). Valproic acid defines a novel class of HDAC inhibitors inducing differentiation of transformed cells. The EMBO journal, 20(24), 6969-6978.

Jeong, S. G., Ohn, T., Kim, S. H., & Cho, G. W. (2013). Valproic acid promotes neuronal differentiation by induction of neuroprogenitors in human bone-marrow mesenchymal stromal cells. Neuroscience letters, 554, 22-27.