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Supercentenarian longevity package deal

$1999.99

A New Approach to Your Health


This first year package contains everything you need to keeping your body vibrant as you age:

One - Whole genome sequencing kit

One - Whole genome bisulfite sequencing kit

One - NAD kit

Two - NMN, Hyaluronic acid, Astaxanthin cream jars

Twelve - 249 mg NMN & 1 mg 5-MTHF supplement bottles (60 Capsules)


This package is specially formulated for you with the most recent human clinical trail studies and most sophisticated technologies available.


With worldwide free shipping!

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Category: packages

There is an old saying, if you love your product, there's a good chance others will too.


This package answers four important questions:

1 - What is my genetic makeup and how can I access that information usefully.

2 - What is my real biological age and how can I reduce it.

3 - What are my NAD levels and am I on the right track.

4 - How do I restore my depleted NAD levels and which supplement should I take.

5 - How to get some results immediately, without waiting months.



1 - What is my genetic makeup and how can I access that information usefully.

Give your self a change to discover who you really are.

With whole-genome sequencing (WGS) you have a comprehensive method for analyzing your entire genomes. With your genomic information at hand you have the key to access imaginable information about your self.

The information you can find is limitless. So what type of information do you want to know about yourself?


-  Identify inherited disorders

-  Characterize mutations that drive cancer progression

-  Find you family tree

-  Information about your nutrition And fitness

- And many more..



2 - What is my real biological age and how can I reduce it.

Get a full picture of your biological age with Whole Genome Bisulfite Sequencing.

It is currently well established that DNA methylation biomarkers can determine biological age of any tissue across the entire human lifespan. And the technology to establish this is called Whole Genome Bisulfite Sequencing.

If you want a full blueprint of your real biological age without skipping any information, then whole genome bisulfite sequencing is the only option.


Information is key and with whole genome bisulfite sequencing you will have the information to start tracking and improving your health and longevity.



3 - What are my NAD levels and am I on the right track.

It is wel known that NAD levels decline as you age and the main goal of NMN supplementation is to restore your depleted NAD levels. But what is your baseline, how do you know your on track., and how do you know your are really restoring your NAD levels.


That way we test our NAD+ levels. With this state of the art NAD test you can conveniently test your NAD levels at home, and be sure that you are taking the right amount and that you are on the right track when it comes to restoring your NAD.



4 -  How do I restore my depleted NAD levels and which supplement should I take.

Gain energy, improve your sleep, restore vitality, and embrace longevity with NMN (Nicotinamide mononucleotide)


Our NMN is formulated with 250mg of NMN (Nicotinamide Mononucleotide) to target the natural decline of NAD+ in our bodies as we age. NMN is one of the most promising supplements for safely and effectively slowing the signs of aging in nearly every organ in the body.


You can also test the NAD+ levels of your loved ones at hand you can upload your data to our website and we can give you an estimate of how much NMN should be taken based on the latest human clinical trail research. 


5 - How to get some results immediately, without waiting months.

Start with your skin. It is the first thing everyone sees so why not use the most potent anti aging molecule, the most potent antioxidant molecule and the most hydrating molecule combined in one face cream to give you the best of both worlds.


Our molecules are known as NMN and Astaxanthin

- NMN to energize the cell

- Astaxanthin to protect the cell


NMN - We believe that your skin cells know exactly what needs to be done. We do not tell the cell what to do we give it what it really needs ENERGY.

Multiple research studies have shown that NMN can help energize the cells from within. Since your skin is getting older it finds it more and more difficult to maintain the energy levels needed to function properly and that is where NMN comes into play.


Astaxanthin is an antioxidant that is considered 6,000 times more powerful than vitamin C. The molecule Astaxanthin scavenges the ROS in the skin surface which ultimately protects and helps reduce moisture loss and keeps skin smooth. Research has sown that Astaxanthine, inhibits collagenases, MMP activity, inflammatory mediators, and ROS induction, resulting in potent anti-wrinkle and antioxidant effects.



Your biological data is worth gold, why not help others.

- If you want you can share your genetic data to aid human identification investigations in order to help law enforcement resolve cases. Yes, your support helps solve crimes, enable the identification of John & Jane Does, and bring closure to families.

- You can even give your data to the research community where it can be used in genomic research.


Together we can even go one step further, 1% of all our profits will be given to a Centenarian charity. This year the money goes to Centenarians of Barbados.

To get the whole picture, sequence the whole genome


 This is how
Workflow
Construction of Sequencing Library
The genome is first prepared, and then the DNA is randomly fragmented into hundreds of bases or shorter fragments with specific adapters at both ends. If the transcriptional group is sequenced, the library construction is a bit more troublesome. After the RNA fragmentation, it needs to reverse to cDNA, then add the connector, or reverse the RNA to the cDNA first, then fragment and add the joint. The size of the fragment (insert size) has an impact on the subsequent data analysis and can be selected according to needs. For genome sequencing, several different insert sizes are usually chosen to get more information when assembling.
Surface Attachment and Bridge Amplification
The reaction of Solexa sequencing is carried out in a glass tube called flow cell, and flow cell is subdivided into 8 Lanes, each of which has a number of fixed single strand joints on the inner surface of each Lane. The DNA fragment of the joint was transformed into a single strand and combined with the primers on the sequencing channel to form a bridge like structure for subsequent preamplification.
Denaturation and Complete Amplification
The unlabeled dNTP and the common Taq enzyme were added for solid phase bridge PCR amplification, and the single-stranded bridge sample was amplified into a double-stranded bridge fragment. By denaturation, a complementary single strand is released and anchored to the nearby solid surface. By continuously cycling, millions of clusters of double-stranded analytes will be obtained on the solid surface of the Flow cell.
Single Base Extension and Sequencing
Four fluorescently labeled dNTPs, DNA polymerases, and linker primers were added to the sequenced flow cells for amplification. When each sequencing cluster extends the complementary strand, each fluorescent labeled dNTP is added to release the corresponding fluorescence. The sequencer obtains sequence information of the fragment to be tested by capturing a fluorescent signal and converting the optical signal into a sequencing peak by computer software. The read length is affected by a number of factors that cause signal attenuation, such as incomplete cutting of fluorescent markers. As the length of the reading increases, the error rate will also increase.
Data Analysis
This step is not strictly a part of the sequencing process, but it only makes sense through the work in front of this step. The raw data obtained by sequencing is a sequence of only a few tens of bases in length, and the contigs that assemble these short sequences through bioinformatics tools are even the framework of the entire genome. Alternatively, these sequences are aligned to an existing genome or a similar species genome sequence, and further analyzed to obtain biologically meaningful results.



Common Techniques Used to Measure DNA Methylation


Technique Advantages
Disadvantages
Affinity enrichment based (e.g., MeDIP and MBD-based methods)
Low cost relative to bisulfite sequencing.
Low resolution relative to bisulfite sequencing. Bias due to copy number variation, GC content, and CpG density. Higher input requirements than bisulfite conversion–based methods.
Bisulfite conversion based (e.g., WGBS, RRBS, and Infinium)
Low input requirements (pg–ng scale). Single-nucleotide resolution. Can provide non-CpG information.
Labor and computation intensive compared with affinity enrichment techniques. Susceptible to bias from incomplete bisulfite conversion and bisulfite PCR artifacts.

Definition of abbreviations: CpG = cytosine-phospho-guanine; GC = guanine-cytosine; MBD = methyl-CpG binding domain protein; MeDIP = methyl-DNA immunoprecipitation; RRBS = reduced representation bisulfite sequencing; WGBS = whole-genome bisulfite sequencing.



The 5 hallmarks of aging affected by lower NAD levels



Hallmarks of aging



1  Epigenetic alteration
Studies have shown that elevating NAD levels can increase telomere length. NAD is also essential for the functions of many proteins involved in regulating gene expression.
2 Loss of proteostasis
Proteostasis is the ability of a cell to make stable, functioning proteins.
3 Deregulated nutrient sensing
Cells respond to the abundance of nutrients in the diet through different pathways. When nutrient sensing is deregulated, cells don’t respond well to nutrients which can lead to conditions such as insulin insensitivity.
4 Senescence Senescent cells are zombe-like cells that stopped dividing and do not function normally. While senescece plays some imortant roles in normal physiology, increased senescence, as observed in many patients with diseases and people with old age, is harmful because senescent cells secrete large amounts of pro-inflammatory molecules and contribute to many age-related diseases.
5 Mitochondrial dysfunction Mitochondria generate energy in the form of the ATP molecule via the Krebs cycle and oxidative phosphorylation. These processes are called respiration and produce free radicals that can harm the cell. As we age our mitochondria become dysfunctional by producing less ATP and more free radicals.



NMN supplement benefits you can expect to see after 1, 3 and 6 months


Time Expected Benefits
After 1 month

Increased and sustained energy 

NMN has been shown to increase blood NAD levels in humans, which is essential for cellular functions such as energy production, defense and repair. NAD levels in our body diminish with age, leading to a decline in cellular energy production.


After 3 months

Improved sleep & physical performance

Supplementing with 250mg NMN over 12 weeks enhances physical function, reduces drowsiness and improves sleep quality. Another study found that 250 mg of NMN enhances muscle function and mobility after 12 weeks.


After 6 months 

Healthier weight, feel & even look younger

Long-term NMN supplementation suppresses age-associated weight gain, enhances energy metabolism, improves insulin sensitivity and prevents age-linked changes in gene expression NMN has been shown to increases telomere lengthin middle-aged adults.




Facts face cream - NMN, Hyaluronic acid and Astaxanthin


Facts

Warnings

FOR EXTERNAL USE ONLY.

• Avoid contact with eyes or mucous membranes.

• Do not apply to wounds or damaged or irritated skin.

• Do not use if skin is sensitive, or have allergies to any ingredients in this  

  product. Discontinue use and consult a doctor if irritation or rash appear.

• In case of ingestion, seek professional assistance or contact a Poison 

  Control Center immediately.

• If pregnant or breast feeding consult a doctor before use.

• Keep out of reach of children.


Active Ingredients
Astaxanthin 2.5% - β-nicotinamide mononucleotide (nmn) 1.2%
Indications
Apply to affected area not more than 2 to 3 times daily. Try on small area first to test for sensitivity.
Other Ingredients
Hyaluronic acid, Dimethicone, Parfume, Propylene Glycol, Diazolidinyl Urea, Methylparaben, Propylparaben

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About Cellulim

After walking trough the ruins of the Mesopotamian civilization our founder realized life is too big to dream small. So he started a company “Cellulim” with a mission to extend human lives in an Alolim economy. After all, life is brimming with possibilities. It’s where “What if” runs away with “Why not?” It’s taking the trail less travels to find a better world. Because deep inside we all feel we can do better, so step up start living again and make this planet a better p>

Phone: 00971585619813

Email:info@cellulim.com